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IC50s (half-maximal inhibitory concentrations) of drugs and gene expression of cancer cell lines were downloaded from the CellMiner database (https://discover.nci.nih.gov/cellminer/home.do). Only drugs with FDA approval or in clinical trials were included in further analyses. Pearson correlation coefficients between YAP1 expression and the IC50 z score of each drug were calculated using the ggpubr R package and represented as bubble plots or scatter plots using the ggplot2 R package.
Copyright and License information: ©2022 Hu, Zhang, Yu, Zhao, Sun, Li and Wang
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