For 215 healthy donors, nucleosome profiling with and without GC correction was performed on the top 10,000 TFBSs for each of 377 TFs. For each TF, the MAD of the central coverage values was calculated both before and after GC correction. For all 377 TFs, the MAD values before and after GC correction were compared using a Wilcoxon signed-rank test (two-sided).
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