Blood samples were collected before and 1, 2, 3, and 4 weeks after surgery, and haematological and biochemical tests were performed to further assess the toxicity of the bone cement. Haematological parameters, including the white blood cell (WBC) count, red blood cell (RBC) count, haemoglobin (HGB), haematocrit (HCT), mean corpuscular volume (MCV), and platelet distribution width (PDW), were analysed with an autohaematology analyser (Mindray BC-2800 Vet, Shenzhen, China). Biochemical parameters, including total protein (TP), albumin (ALB), and blood urea nitrogen (BUN), were tested using an autobiochemistry analyser (Rayto Chemray 800, Shenzhen, China) with a reagent kit for each parameter. Then, the parameters were compared among groups at each time point.
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