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2.6. Functional enrichment analysis
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We generated an interaction network from the STRING5 database by entering all selected key genes, only significant links were preserved and presented in the final figure [12]. In addition, we also performed Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses to reveal major: functions of the selected key genes using "clusterProfiler" package in R, with filter value q < 0.05 [13].
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