Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses were carried out in the promoter regions. DMRs were mapped to GO terms in the database (http://www.geneontology.org/), and the gene numbers for every term were calculated. Then, significantly enriched GO terms were identified on GO TermFinder (https://www.yeastgenome.org/goTermFinder). KEGG pathways analysis were performed with KOBAS software (version 2.0) (Mao et al., 2005). GO terms and KEGG with corrected p ≤ 0.05 were considered to be significantly enriched.
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