2.8. Animal models of tumor

Transfected and untransfected SGC7901 cells were injected into the subcutis of the right axillary of male athymic BALB/c nude mice. Intraperitoneal injection of saline or DADS (100 mg/kg) was performed every 2 days until the end of the experiment. Tumor volume (mm³) was calculated using a standard formula (width² × length × 0.5) every 7 days. Average tumor volumes are displayed (n = 5 for each group) from the 7th day and continued until the 70th day. The weight of the xenograft was measured on the 70th day. All experiments were performed according to the guidelines for animal use of the Ethics Committee of University of South China.