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Human Caucasian hepatocyte carcinoma (HepG2) (Sigma-Aldrich, cat# 85011430) was used for the cytotoxicity experiments. Targeted fractions were assessed for 50% of cytotoxicity (CC50) at concentrations from 200 to 1 μM in triplicate. Cell viability was performed using the MTT assay as described by Crusco et al. (2019).
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