2.2.3 Protein-protein interaction network and crucial subnetwork

JZ Jing Zhou
LL Lisha Li
XP Xinyao Pan
JW Jing Wang
QQ Qing Qi
HS Hongmei Sun
CL Chuyu Li
LW Ling Wang
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A PPI network of core regulatory targets was conducted using the STRING database (https://string-db.org). The species was “Homo sapien” and confidence was 0.4. The PPI network was then imported into Cytoscape 3.8.2 software to retrieve the crucial subnetwork. The Cytohubba and CytoNCA plugin was used to select the top 20 nodes and reconstruct the crucial network.

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