The C57BL/6 mice used in these studies were purchased from Charles River or bred in our colony. Mice were housed in standard polycarbonate/polysulphones cages at 25°C with 12 L:12D cycles and given water and a standard rodent diet ad libitum. All animal experiments were approved by the IACUC of the University of Florida and conducted in accordance with the NIH Guide for the Care and Use of Laboratory Animals.
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