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2.6. Induction of type 2 diabetes mellitus

MK Marwa S. Khattab
TA Tahany A. A. Aly
SM Sara M. Mohamed
AN Abdel Moneim M. Naguib
AA Ammar AL‐Farga
EA Emam A. Abdel‐Rahim
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Rats were fed HFD ad libitum for 2 weeks and then injected intraperitoneal with a single low dose of streptozotocin (STZ) (30 mg/kg) to induce Type 2 DM (Zhang, Lv, Li, Xu, & Chen, 2008). The fasting blood glucose levels of all rats were measured after 7 days of STZ injection. Rats having blood glucose levels ≥200 mg/dl were considered diabetic and were selected for further experiment and maintained on HFD until the end of the experimental period.

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This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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