2. 5. Chemotherapy

Some patients had used several chemotherapy regimens. The most used regimen was cisplatin plus 5-fluorouracil (5-FU). Two cycles of cisplatin (75 mg/m²) on day 1 and 5-FU (800 mg/m²) on days 1 to 4 at were given at 4-week intervals. As for consolidation chemotherapy, 2 cycles of cisplatin (75 mg/m²) on day 1 and 5-FU (800 mg/m²) on days 1 to 4 were given starting approximately 4 weeks after CRT. The second chemotherapy regimen was docetaxel plus carboplatin. Docetaxel (7.5 mg/m²) on day 1 and carboplatin (area under the curve [AUC] = 2) on day 1 was used, and the patients received 4–6 cycles of chemotherapy. The third chemotherapy regimen was docetaxel plus cisplatin. The dosage and administration schedule was intravenous docetaxel (7.5 mg/m²) on day 1 and a continuous infusion of cisplatin (75 mg/m²) on day 1. The chemotherapy cycles were the same as those for docetaxel plus carboplatin.