2.3. GO Enrichment and KEGG Pathway Analysis

YT Yan Teng
SL Sujing Li
YD Yang Ding
YF Yibin Fan
MH Miao He
HL Hengzhen Li
XT Xiaohua Tao
YH Youming Huang
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Gene ontology (GO) analysis is a commonly applied method to define genes and its RNA or protein product to identify unique biological properties of high-throughput transcriptome or genome data. The Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis is a collection of datasets managing the genomes, diseases, biological pathways, drugs, and chemical materials. We utilize the Database for Annotation, Visualization, and Integrated Discovery (DAVID 6.8, https://david.ncifcrf.gov) to perform the GO analysis and KEGG analysis in helping classify the DEGs (P value < 0.05). The GO enrichment analysis comprises biological processes (BP), cellular components (CC), and molecular functions (MF).

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