This study was a retrospective multi-institution cohort study. Patients diagnosed with IBDI in 22 Spanish centers between January 1990 and July 2020 were included in our study. Ethical approval for this study was obtained from the Clinical Research and Ethics Committee at the Virgen de la Arrixaca Clinic and University Regional Hospital Murcia, Spain (Internal Protocol Code: 2021–5-3HCUVA). All the centers completed a uniform data collection protocol with clear variable definitions.
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