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CNV analysis

XF Xin Fan
FX Fei Xie
LZ Lingling Zhang
CT Chang Tong
ZZ Zhiyuan Zhang
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We obtained CNV data for 9 PR-DE-IRFeGs of 512 THCA samples from the UCSC Xena database for our analysis. The analysis mainly included counting and visualizing the CNV frequencies of these genes and their chromosomal locations. For further analysis, the entire samples were split into normal, and single-gain/single-deletion copy groups according to variants of copy numbers in BID and CDKN2A. Then, the differential expression of PR-DE-IRFeGs between 2 groups was assessed. Additionally, survival differences between 2 groups were analyzed by constructing Kaplan-Meier survival plots.

Copyright and License information:  ©2022 Fan, Xie, Zhang, Tong and Zhang.
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