The spontaneous locomotor activity test is used to measure gross and fine motor movements in mice [17]. The aspects of activity measured are horizontal activity such as distance traveled and vertical activity such as vertical and jump counts. In order to assess motor function, mice were monitored for 30 min using the Med Associates spontaneous activity chambers (27.3 [L] × 27.3 [W] × 20.3 [H] cm) with 16 beams (Med Associate Inc).
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