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3.3. Solvent Evaporation Method
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The solvent evaporation method involves the dissolution of both copolymers and drugs in a common solvent or miscible solvents. When both the polymers are dissolved in the solvent and are soluble in the water, this is the method of choice for PM fabrication. A drug-copolymer thin film is formed after the evaporation of the solvents. The addition of water or buffers leads to the spontaneous formation of drug-loaded PMs. Furthermore, processing by a sonicator or high-pressure extruder distributes the size of the micelles equally [42,44].
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