Improve Research Reproducibility A Bio-protocol resource
Concise Method
tooltip

CIOM Induction

OK Oke Kadarullah
DT Didik Gunawan Tamtomo
BW Brian Wasita
MS Made Setiamika
request Request a Protocol
ask Ask a question
Favorite

Twenty male Wistar rats (250 g ± 20 g) were used in this study. The rats were maintained at a controlled room temperature (21 °C ± 2), humidity at approximately 55% ± 10, light and dark cycles every 12 h, and no restriction of food and drink. After a week of acclimation, the rats were randomly divided into the following four groups: control/untreated, and D1 (Cisplatin 3 mg/kgBW), D2 (Cisplatin 5 mg/kgBW), and D3 (Cisplatin 6 mg/kgBW) groups. Cisplatin was administered intraperitoneally (i.p.) on days 1, 3, and 5 (19-22). The control group did not receive anything. The rats were sacrificed on day 14 by guillotine decapitation.

Copyright and License information:  ©2023 Academy of Sciences and Arts of Bosnia and Herzegovina
This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Do you have any questions about this protocol?

Post your question to gather feedback from the community. We will also invite the authors of this article to respond.

0/150

tip Tips for asking effective questions

+ Description

Write a detailed description. Include all information that will help others answer your question including experimental processes, conditions, and relevant images.

post Post a Question
0 Q&A