The transcriptomic and clinical data of BRCA patients were obtained from The Cancer Genome Atlas (TCGA) database. Immunotherapy data of the GSE173839 BRCA cohort was extracted from the Gene Expression Omnibus (GEO). The Molecular Taxonomy of Breast Cancer International Consortium (METABRIC) dataset was downloaded from the cBio cancer genomics portal (cBioPortal). Only samples with complete clinical and survival data were included in the analysis. The transcriptomic and clinical data of the IMvigor210 cohort were extracted using the “IMvigor210CoreBiologies” R package (http://research-pub.gene.com/IMvigor210CoreBiologies/packageVersions/). Ethics committee approval was not required since all data were obtained from public databases. The flow chart is shown in Suppl. Fig. 1.
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