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All data presented in this study were collected and analyzed using SPSS version 25.0 (IBM, USA). We followed the methods of a previous study to analyze the statistical data.22 Disease-free survival (DFS) and OS were defined according to a previous study.23 The independent sample t-test method was used to analyze KDR mRNA expression according to the genotype status of rs2071559. Additionally, Cox analysis was adopted for DFS in the multivariate analysis. P<0.05 was statistically significant.

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