The LEAP trial randomized 640 infants, aged 4 to 11 months with severe eczema, egg allergy, or both, to early peanut introduction or avoidance during early life. These participants encompassed the LEAP screening study groups II and III; each of these 2 cohorts was independently powered, randomized, and analyzed.7 The LEAP trial determined that peanut allergy was prevented in the early introduction group within both cohorts (Table E2).7,17
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