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Spontaneous AP firing

AB Arjun A. Bhaskaran
TG Théo Gauvrit
YV Yukti Vyas
GB Guillaume Bony
MG Melanie Ginger
AF Andreas Frick
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Neurons that spontaneously fired at least one action potential (AP) during a 120-s-time window were considered spontaneously active, otherwise silent. The spontaneous AP rate was calculated as the number of APs elicited during this 120-s-time window. The analysis included data from both active and silent neurons. We acknowledge the limitation of the term “silent”, since these neurons would likely become “active” if we would analyze spontaneous AP firing over a longer time window. As a result, many WT neurons had spontaneous AP firing values of zero and we could therefore not include this feature in our correlation matrix and the accompanying node plot for WT neurons.

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