2.6. Particle Size Distribution

JS Julia Solnier
YZ Yiming Zhang
YK Yun Chai Kuo
MD Min Du
KR Kyle Roh
RG Roland Gahler
SW Simon Wood
CC Chuck Chang
ask Ask a question
Favorite

The Mastersizer 3000 particle size analyzer (Malvern Panalytical, Québec City, QC, Canada) was used to determine the particle size distribution. Briefly, approximately 1 mL or 1 g of the content of the capsules was added into a Hydro SM (Malvern Panalytical, Québec City, QC, Canada) wet dispersion accessory filled with approximately 200 mL of water. Data were collected over a period of 1 min once the dispersed mixture reached 10% obscuration. Hydrodynamic volumes of the resulting particulates (powder-in-water and micelle-in-water mixtures) were determined through laser diffraction data analyzed using the Mastersizer software 3000 (Malvern Panalytical, Québec City, QC, Canada).

Do you have any questions about this protocol?

Post your question to gather feedback from the community. We will also invite the authors of this article to respond.

post Post a Question
0 Q&A