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4.5.1. Systemic Treatment with Risedronate Sodium

BI Bruna Kaori Namba Inoue
LP Laura Vidoto Paludetto
NM Naara Gabriela Monteiro
FB Fábio Roberto de Souza Batista
IK Igor Lebedenco Kitagawa
RS Roberto Santana da Silva
CA Cristina Antoniali
PF Paulo Noronha Lisboa Filho
RO Roberta Okamoto
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Thirty days after SHAM and bilateral ovariectomy, the OVX + HD + RIS group began treatment with risedronate sodium (ApothiMed Ltda., Araçatuba, SP, Brazil) at 35 mg/kg. The drug was diluted in saline solution and administered weekly by gavage using a curved gavage needle (Insight equipment) until the end of the experiment. Animals in the SHAM and OVX + HD groups received the vehicle (saline) only during the same period.

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Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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