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2.8. Construct the Gene Interaction Network
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We used STRING (https://cn.string-db.org/ (accessed on 13 January 2023)) to construct and screen gene interaction networks. This network contained genes with significant functional enrichment associated with muscle development. We only retained network edges that meet the confidence score >0.4. Visualize the gene–gene interaction on input using Cytoscape (v3.9.01), and the strength of gene interactions was reflected by the betweenness algorithm in this software (Supplementary Table S5).
Copyright and License information: ©2023 by the authors.
Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
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