Drugs

For electrophysiology, Octreotide Acetate (Sigma Aldrich, PHR 1880) was dissolved in ddH2O at 3.27 mM, aliquoted at 100 μL, stored at −20°C, and diluted to 3.27 μM as needed. SST (Bachem, H-1490) was dissolved in ddH2O at 1 mM, aliquoted at 50 μL, stored at −20°C, and diluted to 1 μM in aCSF as needed. Cyclosomatostatin (cyclo-SST; Abcam, ab141211) was dissolved in DMSO at 1 mM, aliquoted at 100 μL, stored at −20°C, and diluted to 1 μM in aCSF as needed. Tetrodotoxin (TTX) (Abcam, ab120054) was dissolved in ddH2O at 5 mM, aliquoted at 50 μL, stored at −20°C, and diluted to 500 nM in aCSF as needed. 3 mM Kynurenic acid (Sigma, K3376), 25μM Picrotoxin (Hello Bio, HB0506), and 1μM CGP 55845 (Tocris, 1248) was added to the aCSF as needed. For behavior, Octreotide Acetate (Sigma Aldrich, PHR 1880) was dissolved in sterile aCSF at 327 μM, aliquoted at 100 μL, stored at −20°C, and diluted as needed.