C57BL/6J mice (6- to 8-week-old male) were purchased from the Animal Core Facility of Nanjing Medical University (Nanjing, China). They were housed under the pathogen-free condition with a temperature of 25 ± 2 °C, humidity of 50 ± 5%, and maintained at a 12 h light/dark cycle with free access to food and water.
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