Improve Research Reproducibility A Bio-protocol resource
Concise Method
tooltip

Study objectives

GD Giselle da Silva Duarte
AJ Alexandra D. Jones
LC Luciano Pamplona de Goes Cavalcanti
MR Moacyr Jesus Barreto de Melo Rêgo
GR Guilherme S. Ribeiro
RB Rosemary J. Boyton
DP Dhelio Batista Pereira
JC Julio Henrique Rosa Croda
FC Fabio Trindade Maranhão Costa
AD Angela Pinto Duarte
MC Marcia Edilaine Lopes Consolaro
RS Rodrigo Guerino Stabeli
FN Fábio Juliano Negrão
JP Jose Luiz Proenca-Modena
JV Juan Miguel Villalobos-Salcedo
GP Geraldo da Rocha Castelar Pinheiro
AA Amanda Pinheiro de Barros Albuquerque
FB Francisca Kalline de Almeida Barreto
JM Jose Moreira
IF Idalina Cristina Ferrari
PÉ Patricia Martinez Évora
VS Vânia Ramos Sela da Silva
ML Marcus Vinicius Guimarães Lacerda
DA Daniel M. Altmann
AS André M. Siqueira
ask Ask a question
Favorite

The study’s primary objective is to investigate the natural history and therapeutic response of musculoskeletal manifestations of individuals infected by CHIKV in the Brazilian territory. Its secondary objectives are: 1) to investigate the risk and prognostic factors associated with the severity and persistence of clinical manifestations, 2) to estimate the financial and psychosocial impact of CHIKV, 3) to examine the pathobiology of CHIKV infection during the acute phase, 4) to identify biomarkers that can establish molecular correlations of disease progression and patterns of persistence of joint pain, and 5) to establish a biobank of well-characterized CHIKV samples (specimens), to support the development of new tools to improve diagnosis and prognosis of CHIKV in endemic regions.

Copyright and License information: The Author(s) ©2023
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

Do you have any questions about this protocol?

Post your question to gather feedback from the community. We will also invite the authors of this article to respond.

post Post a Question
0 Q&A