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Secondary outcomes

YJ Yuanyuan Jin
JC Jin Chen
QC Qichen Chai
JZ Jianfang Zhu
XJ Xiaoqing Jin
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Secondary measures will include the MMSE and Functional Activity Questionnaire (FAQ) scores. The MMSE has 11 questions and tests five aspects of cognitive function. The highest score is 30 points, and a score of < 24 points is regarded as abnormal dementia [32]. Daily abilities include basic activities of daily living (BADL) and instrumental activities of daily living (IADL). The former refers to the most basic abilities required for independent living, and the latter refers to complex daily or social activities. The diagnosis of MCI requires normal BADL and slight impairment of IADL. FAQ is a commonly used IADL evaluation scale that has been proven to distinguish between people with normal cognitive function and those with MCI (level II evidence) (Professional Committee of cognitive disorders, Chinese Medical Association, 2018 Chinese guidelines for diagnosis and treatment of dementia and cognitive impairment (V): diagnosis and treatment of mild cognitive impairment 2018) and can be used as an indicator of the transformation from MCI to AD (level II evidence) [33].

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