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This study followed the PRISMA declaration and was registered at PROSPERO (CRD42022377004) [18]. Two independent researchers (XG and RZ) searched Web of Science, PubMed, and EMBASE for eligible papers published before September 1, 2022. The search strategy used was (“atezolizumab” OR “anti-PDL1” OR “MPDL3280A” OR “Tecentriq” OR “RG7446”) AND (“Bevacizumab” OR “Mvasi” OR “Avastin” OR “Bevacizumab awwb”) AND (“Liver cancer” OR “Hepatocellular Carcinoma” OR “Hepatoma” OR “HCC”). There were no restrictions on the search based on geography, race, age, or payment type. In addition, references of potentially eligible articles were investigated for useful studies.

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