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Sensitivity analysis

KT Kaitlin R. Taibl
AD Anne L. Dunlop
DB Dana Boyd Barr
YL Yuan-Yuan Li
SE Stephanie M. Eick
KK Kurunthachalam Kannan
PR P. Barry Ryan
MS Madison Schroder
BR Blake Rushing
TF Timothy Fennell
CC Che-Jung Chang
YT Youran Tan
CM Carmen J. Marsit
DJ Dean P. Jones
DL Donghai Liang
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The PFAS body burden in fetal tissues has been shown to increase with gestational age and is believed to coincide with trans-placental transfer29,128,129. To assess the influence of this hypothesized confounder on the enriched signals and pathways associated with PFAS exposure, we conducted sensitivity analyses without adjusting for the week when the maternal serum sample was collected and compared the results to those obtained in the main analyses. We also performed sensitivity analyses to identify similarities across the enriched pathways associated with PFAS and birth outcomes at the serially reduced significance thresholds, as described above.

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