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PICO question development

FC Fabio Cesare Campanile
MP Mauro Podda
FP Francesca Pecchini
MI Marco Inama
SM Sarah Molfino
MB Marco Augusto Bonino
MO Monica Ortenzi
GS Gianfranco Silecchia
FA Ferdinando Agresta
MC Michela Cinquini
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The panel formulated the questions addressed in this guideline following the PICO criteria (Population, Intervention, Comparison, and Outcome). Several outcomes of interest for each question were identified, and their relative relevance was graded as follows [11, 13]:

Only "critical" or "important" outcomes were considered in the literature review and subsequently in the formulation of recommendations, according to the criteria shown in Table ​Table11.

Relevance of the Outcome measures according to GRADE (Grading of Recommendations, Assessment, Development, and Evaluations)

Included into the evidence table/summary of findings table

Included into the Recommendations

Included into the evidence table/summary of findings table

Not included into the Recommendations

Not included into the evidence table/summary of findings table

Not Included into the Recommendations

From: https://gdt.gradepro.org/app/handbook

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