The GSE169077 dataset in the GEO database (26) (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE169077), which was selected to analyze the differentially expressed genes in OA, was used to analyze ZBTB16 expression in OA tissues. The possible binding of ZBTB16 to the GRK2 promoter was predicted using the Cistrome DB database (version 1.0; http://cistrome.org/db/#/).
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