Improve Research Reproducibility A Bio-protocol resource
Concise Method
tooltip

Risk of bias in individual studies

PY Pan Yang
BX Bin Xuan
GL Gang Li
SQ Senrong Qi
ask Ask a question
Favorite

Two reviewers (Pan Yang and Bin Xuan) independently assessed the quality of the included studies by the EPHPP (Effective Public Health Practice Project) Modified scale with minor modifications [22]. The indicators of quality assessment included the following aspects: (1) study design (number of subjects, gender distribution, and inclusion and exclusion criteria), (2) identification of confounding factors (stain and number of cells evaluated), (3) blind analysis (hide sample information when viewing cells under a microscope), and (4) data analysis (Appropriate statistical methods and analysis of cytotoxicity). According to the above four indicators, the literature was evaluated into three grades: strong (three strong ratings and no weak), weak (with two or more weak ratings), and moderate (all remaining cases).

Copyright and License information: The Author(s) ©2023
Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

Do you have any questions about this protocol?

Post your question to gather feedback from the community. We will also invite the authors of this article to respond.

post Post a Question
0 Q&A