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The study was reviewed by the institutional ethics committee and approved as a clinical audit. In accordance with local policy, informed consent was not required. Patients were included if they had undergone MRI-directed targeted TRUS-guided anterior prostate biopsy in 2011–2014 because of suspicion of anterior tumor on MRI (Chart 1). All patients had undergone previous nontargeted TRUS-guided sectoral biopsy which was negative for carcinoma, but had undergone MRI for further evaluation due to persistent clinical concern for occult neoplasm.
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