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Graphpad Prism9 was used to perform all statistical tests. Data are presented as mean ± SD in Figs. 1, ,2,2, ,33 and and44 and Supplemental Figs. 2A and 3). Data are presented as mean ± SEM in Fig. Fig.6B,6B, C and Supplemental Fig. 5. One-way ANOVA with Tukey’s post-hoc test was used in Figs. Figs.1H,1H, H,2B-D,2B-D, B-D,3,3, ,4C-E4C-E and Supplemental Figs. 3 and 4C-E. Two-way ANOVA with Tukey’s post-hoc test in Fig. Fig.6B,6B, C and Supplemental Fig. 5. In all tests, p < 0.05 was considered significant.
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