Cellular-Based Autograft Preparation

Trinity Elite is a cellular-based allograft developed by Orthofix Medical Inc. Their method for preparation is proprietary. Per the manufacturer, to ensure cellular viability, Trinity Elite is developed through a time-sensitive proprietary aseptic process and controlled rate of freezing (1°C/minute) for optimal cell viability; the tissue goes through cryopreservation and storage in vapor-phase liquid nitrogen at −185°C. The manufacturer quotes that validated quality test methods established the presence of BMP-2, ≥ 70% cell viability, a minimum of 750,000 cells/cc of Trinity Elite—of which, 250,000 are mesenchymal stem cells and 250,000 are osteogenic progenitor cells and bone forming cells.