This study was approved by the Ethics Committee of the West China Hospital of Sichuan University (approval number: 2021-908). All patients provided informed consent and did not undergo chemotherapy or radiotherapy before surgery. The tissue samples collected were analyzed for HPV status using droplet digital PCR (Bio-Rad, USA). The samples were obtained from nine patients with OPSCC, comprising eight primary tumor tissues and five adjacent normal tissues (supplemental information, Table S1).
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