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Statistical analysis

IL Itay Lavy
NE Nir Erdinest
JC Jamel Corredores
DW Denise Wajnsztajn
DS David Smadja
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Statistical analysis was conducted using the Statistical Package for the Social Sciences software 25.0 (SPSS Inc., Chicago, Illinois, USA). An unpaired t-test with a two-tailed was employed to compare pre- and posttreatment measures for each parameter: BCVA, CCT, and ECC.

In all analyses, variances were considered. A two-tailed hypothesis test was applied, and P < 0.05 was deemed statistically significant. A continuous model with two independent study groups was utilized for the sample size calculation. A confidence interval of 0.95 was used, and the statistical power was set at 80%. The total sample size required to detect a significant association was 16 patients, corresponding to 17 eyes.

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