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The study used 6–7-week-old female BALB/c mice procured from the Jackson Laboratory (Bar Harbor, Maine, USA) to validate the model in vivo. We split the mice into eight experimental groups, with five mice per group (N = 5), to analyze weight change and survival. Additionally, for systemic infection analysis of the recombinant RG452 viruses, we formed eight more groups of three mice each (N = 3).
Copyright and License information: ©2024 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group, on behalf of Shanghai Shangyixun Cultural Communication Co., Ltd
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The terms on which this article has been published allow the posting of the Accepted Manuscript in a repository by the author(s) or with their consent.
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