Study selection

All studies published in English language were considered eligible if they fulfilled all the following criteria: (1) they were randomised controlled trials or observational cohort studies, (2) they included adult patients (> 18 years) with chronic liver disease or cirrhosis, (3) the definition of myosteatosis was provided, and (4) the prevalence of myosteatosis was reported. Literature search for relevant studies was performed independently by two reviewers (AK, VL) who determined which studies could be potentially included after having screened titles and abstracts. Each study in the list of the preselected papers was evaluated by two independent reviewers (EC, LC) to determine whether it fulfilled all the inclusion criteria. Exclusion criteria were case reports and review articles as well as studies including patients < 18 years old or patients suffering from non-liver diseases.