2.6.1. Grouping and administration

60 ICR mice were randomly divided into 5 groups, 12 in each group: the control group, model group, positive drug group, raw WP group, and processed WP group. The treatment group was given the corresponding drug by intragastric administration, and the blank group and the model group were given the corresponding volume of normal saline for 14 consecutive days [14]. The specific dosage regimen is shown in Table 1. One hour after administration on the 14th day, the blank group was intraperitoneally injected with normal saline, and the mice in other groups were injected intraperitoneally with 0.5% carrageenan solution to establish a thrombus model (Fig. 1).

Administration dose and regimen.

Experimental design.