This study will be a large-scale, pragmatic, open-label, cluster RCT in which six ICUs will be randomized in a 1:1 ratio to the AI-AntiDelirium group or to the PADIS guidelines group (Fig 1).
AI-AntiDelirium: the Artificial Intelligence Assisted Prevention and Management for Delirium, PADIS guideline: the Pain, Agitation, Delirium, Immobility, and Sleep (PADIS) Guidelines.
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