Demographic characteristics, medical history, medication use, and alcohol/substance use were collected through interviews and questionnaires. Race and ethnicity were self-identified, participants self-identified as ‘White’, ‘Black or African American’, ‘Native Hawaiian or other Pacific Islanders’ and ‘Multiple Races’. For analysis purposes, we combined the latter three into one variable, resulting in two race categories. Body mass index (BMI) was calculated using current height and weight. The Alcohol Use Disorders Identification Test (AUDIT), a 10-item screening tool, provided a total score for alcohol consumption (range 0–40) [19]. Apolipoprotein E (APOE) genotyping was performed to identify carriers and non-carriers of the APOE-ε4 allele. The revised Framingham Stroke Risk Profile (rFSRP) score was calculated to determine vascular risk factors. [20] Other relevant medical history included a self-reported questionnaire on sleep apnea diagnosis.
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