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2.8.2. WNK and placebo preparation

JL Junguang Liu
DC Dennis Chang
DC Dennis Cordato
KL Kien Lee
HD Hugh Dixson
AB Alan Bensoussan
DC Daniel Kam Yin Chan
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The Research Centre, Xiyuan Hospital, China Academy of Chinese Medical Sciences, developed the formula for WNK and the placebo. Tianjin Zhongxin Pharmaceutical Group Co. Ltd., a pharmaceutical manufacturer in China with an Australian Good Manufacturing Practice license, prepared the trial medications. The placebo was prepared and designed to taste, smell, and look the same as the Chinese herb medicine (CHM) formulation.

WNK and the placebo were in the form of capsules pre‐packaged in blister packs each containing 60 mg of the active ingredients (ratios of the ingredients by weight being 5:5:1 with the least amount being saffron). The dosage of the WNK in the clinical trial was one capsule, three times daily by oral administration.

Copyright and License information:  ©2022 The Authors. published by Beijing Hospital and John Wiley & Sons Australia, Ltd.
This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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