Improve Research Reproducibility A Bio-protocol resource
Concise Method
tooltip

Statistical analysis

WZ Wei Zhang
ZZ Zongxin Zhang
LQ Lihong Qian
ask Ask a question
Favorite

Combined HR and 95% CI were determined to evaluate whether CRP could be used to predict the prognosis of patients with OC. Heterogeneity across the included studies was explored using Cochran’s Q test and the I2 statistic. Studies with I2 > 50% and/or p < 0.10 indicated obvious heterogeneity; accordingly, combined HR was calculated using a random-effects model; otherwise, a fixed-effects model was used. Subgroup analyses according to different factors were performed to identify potential sources of heterogeneity. In addition, the relationship between CRP level(s) and clinicopathological factors in patients with OC was assessed using a combined odds ratio (OR) and corresponding 95% CI. Funnel plot symmetry was visually inspected to assess publication bias using Begg’s and Egger’s tests. Statistical analysis was performed using Stata version 12.0 (StataCorp LLC, College Station, TX, USA). Differences with p < 0.05 were considered to be statistically significant.

Copyright and License information: The Author(s) ©2024
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

Do you have any questions about this protocol?

Post your question to gather feedback from the community. We will also invite the authors of this article to respond.

post Post a Question
0 Q&A