We utilized ssGSEA [15] to investigate the relationship between SLC10A3 and 24 types of immune cell infiltration in the immune microenvironment of CRC. Furthermore, we examined the differences in immune cell abundance between the high and low SLC10A3 expression groups. Using the Tumor Immune Estimation Resource (TIMER) [16], we assessed the association between the expression levels of tumor-infiltrating immune cells, including B cells, CD4 + T cells, CD8 + T cells, neutrophils, macrophages, dendritic cells, and cancer-associated fibroblasts (CAFs), and SLC10A3 expression. The Pearson method was used to display the results. Finally, we explored the correlation between somatic copy number alterations (SCNA) of SLC10A3 and the abundance of 6 leukocytes using the ‘SCNA module’.
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