All study protocols were approved by the Ethics Review Board of Aravind Medical Research Foundation of India and the Hospital of the University of Electronic Science and Technology of China and the Sichuan Provincial People’s Hospital, and all experiments were performed in accordance with the approved protocols. Fourteen families with arRP, 100 patients with sporadic RP and 1000 control individuals with no history of retinal diseases were recruited in this study. Samples were collected from the Aravind Eye Hospital of India. Written informed consent was obtained from all individuals who participated in this study or from their legal guardians in the case of minors. Venous blood samples were obtained from all subjects in EDTA vacutainers.
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