Genotype data

CB Camillo Bérénos
PE Philip A. Ellis
JP Jill G. Pilkington
JP Josephine M. Pemberton
ask Ask a question
Favorite

Individuals were genotyped using the Ovine SNP50 BeadChip (Illumina) using an iScan instrument at the Wellcome Trust Clinical Research Facility Genetics Core (Edinburgh, UK). Quality control was performed in plink (Purcell et al. 2007). Individuals with call rate >95% were retained, and loci with minor allele frequency <0.01, call rate <99%, or which deviated from Hardy–Weinberg equilibrium (HWE) at P < 1e‐05 were all discarded. A total of 5805 individuals and 37 037 autosomal SNP loci passed quality control. Median spacing between SNPS was 50.2 Kb, and neighbouring SNPs were generally in high linkage disequilibrium (LD, mean r 2 = 0.3).

Do you have any questions about this protocol?

Post your question to gather feedback from the community. We will also invite the authors of this article to respond.

post Post a Question
0 Q&A