Protein–Protein Interaction Network Analysis

TX Tao Xie
YP Yongyan Pei
PS Peijia Shan
QX Qianqian Xiao
FZ Fei Zhou
LH Liuqing Huang
SW Shi Wang
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Use STRING 11.56 to analyze the functional connection and interaction of the encoded gene proteins in miRNA-mRNAs. Keep interaction pairs with confidence ≥ 0.4. Then use Cytoscape 3.9.0 to construct a PPI network. Subsequently, the Cytoscape plug-in Molecular Complex Detection (MCODE) was used to screen sub-networks and hub mRNAs.

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