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2.3. Differentially expressed genes (DEGs) screening
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The “limma” (linear models for microarray data) R package was used to screen the DEGs between normal kidney and clear cell renal cell carcinoma. The SAM (significance analysis of microarrays) with FDR (false discovery rate) < 0.05 and | log2 fold change (FC)| > 0.585 were chosen as the cut-off criteria to select genes further considered in the network construction.
Copyright and License information: ©2017 The Authors
This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
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